Safety data for propanone

Click here for data on propanone in student-friendly format, from the HSci project

Glossary of terms on this data sheet.

The information on this web page is provided to help you to work safely, but it is intended to be an overview of hazards, not a replacement for a full Material Safety Data Sheet (MSDS). MSDS forms can be downloaded from the web sites of many chemical suppliers.

General

Synonyms: dimethyl ketone, methyl ketone, 2-propanone, beta-ketopropane, acetone, dimethylketal, pyroacetic acid, dimethylformaldehyde, pyroacetic ether
Molecular formula: (CH₃)₂CO
CAS No: 67-64-1
EC No: 200-662-2
Annex I Index No: 606-001-00-8
InChI: InChI=1S/C3H6O/c1-3(2)4/h1-2H3

Physical data

Appearance: colourless liquid with a fragrant, sweet odour
Melting point: -95 C
Boiling point: 56 C
Vapour density: 2.0
Vapour pressure: 181 mm Hg at 20 C
Specific gravity: 0.79
Flash point: -18 C
Explosion limits: 2.6% - 13.0%
Autoignition temperature: 538 C

Stability

Stable. Incompatible with halogen acids and halogen compounds, strong bases, strong oxidizing agents, caustics, amines and ammonia, chlorine and chlorine compounds, strong acids, nitrosyl compounds. Highly flammable. Readily forms explosive mixtures with air.

Toxicology

May be harmful by inhalation, ingestion or skin absorption. Irritant. Liquid may cause permanent eye damage (corneal clouding). Contact with skin may cause defatting, leading to irritation. Long-term exposure may cause liver damage. Typical TLV 750 ppm. Typical OEL 250 ppm.

Toxicity data
(The meaning of any abbreviations which appear in this section is given here.)
UNR-MAN LDLO 1159 mg kg^-1
ORL-RAT LD50 5800 mg kg^-1
IHL-RAT LC50 50100 mg m ^-3 / 8h
ORL-MUS LD50 3000 mg kg^-1
IHL-MUS LC50 44 g m ^-3 / 4h

Irritation data
(The meaning of any abbreviations which appear in this section is given here.)
EYE-HMN 500 ppm
SKN-RBT 395 mg open mld
EYE-RBT 20 mg sev

Risk phrases
(The meaning of any risk phrases which appear in this section is given here.)
R11 R36 R66 R67. (Previously categorized as harmful by inhalation, ingestion or skin absorption, but Annex I does not include these risk phrases. Norway still categorizes propanone as harmful by inhalation. Possibility of corneal clouding suggests that R41 might also be specified.)

Environmental information

L. macrochirus

Transport information

here.)

Personal protection

Safety glasses. Good ventilation. Remove sources of ignition from the working area. Butyl rubber gloves.

Safety phrases
(The meaning of any safety phrases which appear in this section is given here.)
S9 S16 S26.

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This information was last updated on February 11, 2009. We have tried to make it as accurate and useful as possible, but can take no responsibility for its use or misuse, or for the accuracy of the information.

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