Safety data for tetrahydrofuran
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Toxicity data
Risk phrases
Safety phrases
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This information was last updated on August 24, 2009. Although
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for it. General
Synonyms: THF, 1,4-epoxybutane, butylene oxide,
cyclotetramethylene oxide, oxacyclopentane,
diethylene oxide, oxolane, furanidine, hydrofuran, agrisynth THF
Molecular formula: C4H8O
CAS No: 109-99-9
EC No: 203-726-8
Annex I Index No: 603-025-00-0
Physical data
Appearance: colourless liquid with ether-like odour
Melting point: -108 C
Boiling point: 66 C
Vapour density: 2.5
Vapour pressure: 129 mm Hg at 20 C
Specific gravity: 0.89
Flash point: -14 C
Explosion limits: 1.5% - 12%
Autoignition temperature: 610 F
Stability
Stable. Incompatible with halogens, strong oxidizing agents, strong
reducing agents, strong bases, oxygen. May generate explosive peroxides in storage if
in contact with air. Highly flammable. Store at room temperature under nitrogen.
Hazardous polymerisation may occur. Light sensitive. May contain
2,6-di-tertbutyl-4-methylphenol (BHT) as a stabiliser.
Toxicology
May be harmful by inhalation, ingestion or skin absorption.
Skin contact may cause dermatitis. Long-term exposure may lead
to kidney or liver damage. Irritant. May cause narcotic effects.
TLV 200 ppm.
(The meaning of any abbreviations which appear in this section is given
here.)
ORL-RAT LD50 2816 mg kg-1
IHL-RAT LC50 62 mg kg-1
IPR-RAT LD50 2900 mg kg-1
IPR-MUS LD50 1900 mg kg-1
ORL-GPG LD50 2300 mg kg-1
(The meaning of any risk phrases which appear in this section is given
here.)
R11 R19 R36 R37.
Transport information
(The meaning of any UN hazard codes which appear in this section
is given
here.)
UN No 2056. Packing group II. Hazard class 3.0.
Transport category 2.
Personal protection
Safety glasses, nitrile gloves. Effective ventilation.
(The meaning of any safety phrases which appear in this section is given
here.)
S16 S29 S33.