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Toxicity data
Risk phrases
Safety phrases
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This information was last updated on May 3, 2006.
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for it. General
Synonyms: 7-chloro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one,
1-methyl-5-phenyl-7-chloro-1,3-dihydro-2H-1,4-benzodiazepin-2-one,
methyl diazepinone,
alboral, aliseum, amiprol, an-ding, ansiolisina, apaurin, apozepam, assival,
atensine, atilen, bialzepam, calmocitene, calmpose, cercine, ceregulart,
cristalia, diapam, diazepam, diazetard, dienpax, dipezona, domalium, duxen,
eridan, faustan, freudal, horizon, kabivitrum, kiatrium, lembrol, levium,
liberetas, morosan, noan, paxate, paxel, quievita, relaminal, relanium,
renborin, saromet, sedipam, seduxen, serenamin, serenzin, setonil, sibazon,
sonacon, stesolid, stesolin,
further trade names
Use: sedative
Molecular formula: C16H13ClN2O
CAS No: 439-14-5
EC No: 207-122-5
Physical data
Appearance: light yellow or cream crystalline powder
Melting point: 125 C
Boiling point:
Vapour density:
Vapour pressure:
Specific gravity:
Flash point:
Explosion limits:
Autoignition temperature:
Stability
Stable. Light-sensitive. Incompatible with strong oxidizing agents.
Toxicology
Harmful by ingestion and through skin contact. May be harmful if inhaled.
May cause allergic reactions. May cause systemic effects. Experimental
teratogen and mutagen in laboratory animals. May cause reproductive defects (LPTD ORAL
WMN 5 mg/kg 36 weeks). May be addictive. Skin,
eye and respiratory irritant.
(The meaning of any toxicological abbreviations which
appear in this section is given
here.)
ORL-RAT LD50 249 mg kg-1
IPR-RAT LD50 47 mg kg-1
IVN-MAN TDLO 143 ug kg-1
ORL-RBT LD50 454 mg kg-1
ORL-MAN TDLO 143 mg kg-1
SCU-MUS LD50 300 mg kg-1
IVN-RAT LD50 32 mg kg-1
(The meaning of any risk phrases which appear in this section is
given
here.)
R20 R21 R36 R37 R38.
Transport information
(The meaning of any UN hazard codes which appear in this section
is given
here.)
UN No 2811. Hazard class 6.1. Packing group III.
Personal protection
Safety glasses, gloves, adequate ventilation.
(The meaning of any safety phrases which appear in this section
is given here.)
S36 S37.